This study focuses with the objective of, determining the proportion of men and women illnesses receiving antihypertensive, studying the prescription pattern for the above illnesses in a primary care setting and determining the factors related to antihypertensive prescription pattern. The study aimed to describe the prevalence of antihypertensive agent use in hospitalized patients. This was a prospective study for a period of three months (Jan, 2010 to Mar, 2010). Data were collected by reviewing medical charts of all patients. All the patients receiving antihypertensive agent were identified and included in the study. Patient information was obtained on a specially designed patient profile form. The documented cases were analyzed to assess the prescribing pattern of antihypertensive and compared with the developed criteria with respect to indication, dose, frequency, route of administration, duration of therapy and potential drug interaction. This study revealed that most of the patients were on combination therapy (58.88 %). In the monotherapy category, six classes of drugs were used. These were calcium channel blockers (40.38 %), beta-blockers (18.26 %), ACE inhibitors/ angiotensin antagonist (25.96 %), other adrenergic blocker (1.92 %), vasodilator (2.88 %) and diuretics (10.57 %). Among monotherapy drugs, calcium channel blockers were prescribed most whereas other adrenergic blocker were least used. This study has shown that antihypertensive prescription rates can be derived from analysis of regional drug and resident databases. High antihypertensive usage is shown in the obese population of Kanpur, similar to that observed in other regions of Northern India. Beta Blockers class of antihypertensive are predominantly prescribed. Diagnostic and therapeutic guides and protocols on hypertension treatment were available at the time of the study, and the drugs of choice and appropriate single-drug and multi-drug regimens were well recognized.
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